Medical & Scientific Research
The Science Behind the Healing Power of Barley Grass
Explore the clinical evidence behind the health benefits of I AM Amazing Barley.
We believe in nature—and
we honor science.
Below is a curated list of peer-reviewed studies that support the functional benefits of young barley grass, the sole ingredient in I AM Amazing Barley. These studies examine its effects on:
- Blood Sugar & Cholesterol
- Inflammation & Antioxidant Defense
- Detoxification & Liver Support
- Neurological & Emotional Balance
- Cellular Health & Disease Prevention
Each reference is linked to its original publication on PubMed, ScienceDirect, or its respective journal—so you can explore the science for yourself.
Peer-Reviewed Scientific Research on Barley Grass
1. Preventive and Therapeutic Role of Functional Ingredients of Barley Grass for Chronic Diseases in Human Beings.
Zeng, Y., Pu, X., Yang, J., Li, L., Zhou, Y., Yang, T., Du, J., Yang, X., Li, X. (2018). Oxidative Medicine and Cellular Longevity, 2018, Article ID 3232080, 15 pages.
DOI: https://doi.org/10.1155/2018/3232080
Highlights: Reviews GABA, flavonoids, SOD, chlorophyll, and vitamins in barley grass, supporting antioxidant, anti-inflammatory, antidiabetic, and liver-protective effects.
2. Mechanism of Functional Ingredients in Barley to Combat Human Chronic Diseases.
Zeng, Y., Pu, X., Du, J., Yang, X., Li, X., Mandal, M.S.N., Yang, T., Yang, J. (2020). Oxidative Medicine and Cellular Longevity, 2020, Article ID 3836172, 26 pages.
DOI: https://doi.org/10.1155/2020/3836172
Highlights: Explains how GABA, flavonoids, and SOD in barley grass target over 20 chronic diseases, including diabetes, obesity, and cardiovascular disorders.
3. Effect of Barley Grass on Antioxidant Capacity and DNA Damage in Diabetic Rats.
Comba, A., Mis, L., Sarıpınar Aksu, D., Basbugan, Y., Comba, B. (2023). Hitit Medical Journal, 5(3), 149–155.
DOI: https://doi.org/10.52827/hititmedj.1281145
Highlights: In diabetic rats, barley grass juice lowered glucose, HbA1c, and oxidative stress while improving antioxidant status, without increasing DNA damage.
4. Effect of Barley on Variation of Blood Glucose and Lipid Metabolism.
Yoo, Y.S., Lee, K.S., Cho, K.H., Kim, D.H., Park, C.H., Lee, S.H., Lee, J.H. (2009). Korean Journal of Family Medicine, 30(10), 790–795.
DOI: https://doi.org/10.4082/kjfm.2009.30.10.790
Highlights: A clinical trial showing barley bread reduces postprandial glycemic response compared to wheat bread, with no significant change in lipid profile.
5. Health Benefits of Barley for Diabetes.
Idehen, E., Wang, W., Sang, S. (2020). Journal of Food Bioactives, 12, 76–86.
DOI: https://doi.org/10.31665/JFB.2020.12246
Highlights: Summarizes evidence that β-glucan, SCFAs, and phytochemicals in barley improve glycemic control, insulin sensitivity, and gut-derived metabolic benefits.
6. Management of Diabetic Dyslipidemia with Subatmospheric Dehydrated Barley Grass Powder.
Venugopal, S., Iyer, U.M. (2010). International Journal of Green Pharmacy, 4(4), 251–256.
DOI: 10.4103/0973-8258.74134
Highlights: In type 2 diabetics, barley grass powder improved fasting glucose, HbA1c, and lipid profile, raising HDL and reducing LDL and total cholesterol.
7. Effect of Barley on Postprandial Blood Glucose Response and Appetite in Healthy Individuals: A Randomized, Double-Blind, Placebo-Controlled Trial.
Kim, I.-S., Park, S.-Y., Park, M.J., Kim, K.J., Kim, J.Y. (2024). Nutrients, 16(22), 3899.
DOI: https://doi.org/10.3390/nu16223899
Highlights: β-glucan-rich barley fiber delayed postprandial glucose and insulin spikes, increased satiety, and reduced hunger via appetite hormone modulation.
8. Barley Grass Extract Causes Apoptosis of Cancer Cells by Increasing Intracellular Reactive Oxygen Species Production.
Woo, S.M., Kwon, S.-C., Ko, S.G., Cho, S.-G. (2017). Biomedical Reports, 6(6), 681–685.
DOI: https://doi.org/10.3892/br.2017.897
Highlights: Demonstrates ROS-dependent apoptosis in breast and prostate cancer cells after barley grass extract exposure, reversible by antioxidants.
9. Young Barley Indicates Antitumor Effects in Experimental Breast Cancer In Vivo and In Vitro.
Kubatka, P., Kello, M., Kajo, K., et al. (2016). Nutrition and Cancer, 68(4), 611–621.
DOI: https://doi.org/10.1080/01635581.2016.1154577
Highlights: In vitro and rat studies show young barley inhibits tumor growth, reduces proliferation, induces apoptosis, and improves lipid profile.
10. Searching in Mother Nature for Anti-Cancer Activity: Anti-Proliferative and Pro-Apoptotic Effect Elicited by Green Barley on Leukemia/Lymphoma Cells.
Robles-Escajeda, E., Lerma, D., Nyakeriga, A.M., et al. (2013). PLOS ONE, 8(9), e73508.
DOI: https://doi.org/10.1371/journal.pone.0073508
Highlights: Green barley extract selectively inhibits proliferation and induces apoptosis in leukemia/lymphoma cells via caspase activation and PARP cleavage.
11. Antioxidative and Hypolipidemic Effects of Barley Leaf Essence in a Rabbit Model of Atherosclerosis.
Yu, Y.M., Wu, C.H., Tseng, Y.H., Tsai, C.E., Chang, W.C. (2002). Japanese Journal of Pharmacology, 89(2), 142–148.
DOI: https://doi.org/10.1254/jjp.89.142
Highlights: Barley leaf essence lowered cholesterol, triglycerides, and oxidative stress in rabbits while enhancing LDL oxidation resistance and reducing aortic lesions.
12. Bioactivity Evaluations of Leaf Extract Fractions from Young Barley Grass and Correlation with Their Phytochemical Profiles.
Panthi, M., Subba, R.K., Raut, B., Khanal, D.P., Koirala, N. (2020). BMC Complementary Medicine and Therapies, 20, 64.
DOI: https://doi.org/10.1186/s12906-020-2862-4
Highlights: Methanolic and ethyl acetate extracts showed high phenolic content, strong antioxidant and anti-inflammatory activity, and multiple bioactive compounds.
13. Investigation of in vitro Biological Activity of Young Hordeum vulgare Leaf in Correlation with Its Bioactive Compounds.
Lantos, F., Váczi, V., Gyalai, I., et al. (2024). Journal of Applied Biomedicine.
DOI: https://doi.org/10.1007/s42977-024-00227-1
Highlights: Methanolic extracts had significantly higher antioxidant activity and moderate xanthine oxidase inhibition, highlighting importance of harvest stage and extraction method.
14. Biological and Molecular Studies of Phytoconstituents from Hordeum vulgare L. Leaves: Potential Treatment for Prostate (DU-145) and Skin Cancer (B16-F10) Cell Line.
Kangra, K., Mujwar, S., Kakkar, S., et al. (2025). Beni-Suef University Journal of Basic and Applied Sciences.
DOI: https://doi.org/10.1186/s43088-025-00623-z
Highlights: Chloroform extract showed strong antioxidant, anti-inflammatory, and cytotoxic effects, with octadecenoic acid as a promising MAPK inhibitor for skin cancer.
15. Barley Grass Juice (Hordeum vulgare L.) Inhibits Obesity and Improves Lipid Profile in High-Fat Diet-Induced Rat Model.
Thatiparthi, J., Dodoala, S., Koganti, B., Prasad, K.V.S.R.G. (2019). Journal of Ethnopharmacology, 238, 111843.
DOI: https://doi.org/10.1016/j.jep.2019.111843
Highlights: In rats on a high-fat diet, barley grass juice reduced body weight, improved lipid and liver markers, boosted antioxidant enzymes, and reduced obesity-related gene expression.
16. Barley Leaf Ameliorates Citrobacter rodentium-Induced Colitis through Preventive Effects.
Feng, Y., Li, D., Ma, C., Tian, M., Hu, X., Chen, F. (2022). Nutrients, 14(18), 3833.
DOI: https://doi.org/10.3390/nu14183833
Highlights: Pre-treatment with barley leaf in a mouse model of colitis reduced disease severity, inflammation, and harmful bacterial load while improving gut microbiota balance.
Want to see how this research translates into real healing?
Discover how I AM Amazing Barley brings this science to life—from blood sugar balance to nervous system support. See why so many are making it part of their daily healing routine.